Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly
Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Ribosome biogenesis requires multiple assembly factors. InEscherichia coli, deletion of RlmE, the methyltransferase responsible for the 2′-O-methyluridine modification at position 2552 (Um2552) in helix 92 of the 23S rRNA, results in slow growth and accumulation of the 45S particle. We demonstrate that the 45S particle that accumulates in ΔrlmEis a...
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Full title
Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly
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TN_cdi_crossref_primary_10_1073_pnas_1506749112
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1506749112
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1506749112
