Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resinife...
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The transient receptor potential cation channel subfamily V member 1 (TRPV1) or vanilloid receptor 1 is a nonselective cation channel that is involved in the detection and transduction of nociceptive stimuli. Inflammation and nerve damage result in the up-regulation of TRPV1 transcription, and, therefore, modulators of TRPV1 channels are potentiall...
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Full title
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin
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TN_cdi_crossref_primary_10_1073_pnas_1517288113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1517288113
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1517288113
