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Identification of tissue-specific cell death using methylation patterns of circulating DNA

Identification of tissue-specific cell death using methylation patterns of circulating DNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1519286113

Identification of tissue-specific cell death using methylation patterns of circulating DNA

About this item

Full title

Identification of tissue-specific cell death using methylation patterns of circulating DNA

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.E1826-E1834

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Minimally invasive detection of cell death could prove an invaluable resource in many physiologic and pathologic situations. Cell-free circulating DNA (cfDNA) released from dying cells is emerging as a diagnostic tool for monitoring cancer dynamics and graft failure. However, existing methods rely on differences in DNA sequences in source tissues,...

Alternative Titles

Full title

Identification of tissue-specific cell death using methylation patterns of circulating DNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_1519286113

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_1519286113

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1519286113