L-type Ca 2+ channel blockers promote vascular remodeling through activation of STIM proteins
L-type Ca 2+ channel blockers promote vascular remodeling through activation of STIM proteins
About this item
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Author / Creator
Publisher
United States
Journal title
Language
English
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Publisher
United States
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Scope and Contents
Contents
Voltage-gated L-type Ca
channel (Ca
1.2) blockers (LCCBs) are major drugs for treating hypertension, the preeminent risk factor for heart failure. Vascular smooth muscle cell (VSMC) remodeling is a pathological hallmark of chronic hypertension. VSMC remodeling is characterized by molecular rewiring of the cellular Ca
signaling machinery, i...
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Full title
L-type Ca 2+ channel blockers promote vascular remodeling through activation of STIM proteins
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Record Identifier
TN_cdi_crossref_primary_10_1073_pnas_2007598117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2007598117
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2007598117
