APPsα rescues impaired Ca 2+ homeostasis in APP- and APLP2-deficient hippocampal neurons
APPsα rescues impaired Ca 2+ homeostasis in APP- and APLP2-deficient hippocampal neurons
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Publisher
United States
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Language
English
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United States
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Contents
Alterations in Ca
homeostasis have been reported in several in vitro and in vivo studies using mice expressing the Alzheimer's disease-associated transgenes, presenilin and the amyloid precursor protein (APP). While intense research focused on amyloid-β-mediated functions on neuronal Ca
handling, the physiological role of APP and its close ho...
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Full title
APPsα rescues impaired Ca 2+ homeostasis in APP- and APLP2-deficient hippocampal neurons
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TN_cdi_crossref_primary_10_1073_pnas_2011506118
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_2011506118
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2011506118
