Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocy...
Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocytes in vitro
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Washington, DC: National Academy of Sciences of the United States of America
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English
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Washington, DC: National Academy of Sciences of the United States of America
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Cytoplasts of mouse L929 and Ehrlich ascites tumor cells harbor DNA sequences that induce unlimited proliferation ("immortalization") of human lymphocytes after transfection in vitro. By equilibrium centrifugation of cytoplasmic lysates in a neutral CsCl gradient, the immortalizing activity was recovered together with extramitochondrial fractions a...
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Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocytes in vitro
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TN_cdi_crossref_primary_10_1073_pnas_90_14_6518
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_90_14_6518
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.90.14.6518