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Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocy...

Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_90_14_6518

Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocytes in vitro

About this item

Full title

Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocytes in vitro

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (14), p.6518-6522

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Cytoplasts of mouse L929 and Ehrlich ascites tumor cells harbor DNA sequences that induce unlimited proliferation ("immortalization") of human lymphocytes after transfection in vitro. By equilibrium centrifugation of cytoplasmic lysates in a neutral CsCl gradient, the immortalizing activity was recovered together with extramitochondrial fractions a...

Alternative Titles

Full title

Short DNA Sequences from the Cytoplasm of Mouse Tumor Cells Induce Immortalization of Human Lymphocytes in vitro

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_90_14_6518

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_90_14_6518

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.90.14.6518

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