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ArticlesPeer ReviewedFull Text
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells
Author / Creator:Bunse, Mario ; Pfeilschifter, Janina ; Bluhm, Julia ; Zschummel, Maria ; Joedicke, Jara J. ; Wirges, Anthea ; Stark, Helen ; Kretschmer, Vivien ; Chmielewski, Markus ; Uckert, Wolfgang ; Abken, Hinrich ; Westermann, Jörg ; Rehm, Armin ; Höpken, Uta E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.240-240, Article 240
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Nanobody Based Dual Specific CARs
Author / Creator:De Munter, Stijn ; Ingels, Joline ; Goetgeluk, Glenn ; Bonte, Sarah ; Pille, Melissa ; Weening, Karin ; Kerre, Tessa ; Abken, Hinrich ; Vandekerckhove, Bart
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-01, Vol.19 (2), p.403
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Weal and woe of interleukin-18 in the T cell therapy of cancer
Author / Creator:Kessel, Christoph ; Rossig, Claudia ; Abken, Hinrich
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2025-01, Vol.13 (1), p.e010545
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Chimeric antigen receptors designed to overcome transforming growth factor‐β‐mediated repression in the adoptive T‐cell therapy of solid tumors
Author / Creator:Hartley, Jordan ; Abken, Hinrich
Publisher:Australia: John Wiley & Sons, Inc
Journal title:Clinical & translational immunology, 2019, Vol.8 (6), p.e1064-n/a
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FimH-based display of functional eukaryotic proteins on bacteria surfaces
Author / Creator:Chmielewski, Markus ; Kuehle, Johannes ; Chrobok, Danuta ; Riet, Nicole ; Hallek, Michael ; Abken, Hinrich
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-06, Vol.9 (1), p.8410-8410, Article 8410
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IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells
Author / Creator:Hombach, Andreas A. ; Geumann, Ulf ; Günther, Christine ; Hermann, Felix G. ; Abken, Hinrich
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-04, Vol.9 (4), p.873
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Design and Characterization of an “All-in-One” Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines
Author / Creator:Zimmermann, Katharina ; Kuehle, Johannes ; Dragon, Anna Christina ; Galla, Melanie ; Kloth, Christina ; Rudek, Loreen Sophie ; Sandalcioglu, I. Erol ; Neyazi, Belal ; Moritz, Thomas ; Meyer, Johann ; Rossig, Claudia ; Altvater, Bianca ; Eiz-Vesper, Britta ; Morgan, Michael Alexander ; Abken, Hinrich ; Schambach, Axel
Publisher:MDPI
Journal title:Cancers, 2020-02, Vol.12 (2), p.375
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Eradication of melanomas by targeted elimination of a minor subset of tumor cells
Author / Creator:Schmidt, Patrick ; Kopecky, Caroline ; Hombach, Andreas ; Zigrino, Paola ; Mauch, Cornelia ; Abken, Hinrich
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (6), p.2474-2479
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Anti-CD19 CAR T cells potently redirected to kill solid tumor cells
Author / Creator:Ambrose, Christine ; Su, Lihe ; Wu, Lan ; Dufort, Fay J. ; Sanford, Thomas ; Birt, Alyssa ; Hackel, Benjamin J. ; Hombach, Andreas ; Abken, Hinrich ; Lobb, Roy R. ; Rennert, Paul D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-03, Vol.16 (3), p.e0247701-e0247701
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International Regensburg Center for Interventional Immunology (RCI) symposium on “Synthetic immunology and environment-adapted redirection of T cells”, 17–18 July, 2019, Regensburg, Germany
Author / Creator:Beckhove Philipp ; Edinger Matthias ; Feuerer Markus ; Gattinoni Luca ; Abken Hinrich
Publisher:Heidelberg: Springer Nature B.V
Journal title:Cancer immunology, immunotherapy, 2020-04, Vol.69 (4), p.677-682
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Chimeric Antigen Receptor (CAR) T Cells Releasing Soluble SLAMF6 Isoform 2 Gain Superior Anti-Cancer Cell Functionality in an Auto-Stimulatory Fashion
Author / Creator:Harrer, Dennis Christoph ; Schlierkamp-Voosen, Tim ; Barden, Markus ; Pan, Hong ; Xydia, Maria ; Herr, Wolfgang ; Dörrie, Jan ; Schaft, Niels ; Abken, Hinrich
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2025-06, Vol.14 (12), p.901
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Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection
Author / Creator:Lehner, Manfred ; Götz, Gabriel ; Proff, Julia ; Schaft, Niels ; Dörrie, Jan ; Full, Florian ; Ensser, Armin ; Muller, Yves A. ; Cerwenka, Adelheid ; Abken, Hinrich ; Parolini, Ornella ; Ambros, Peter F. ; Kovar, Heinrich ; Holter, Wolfgang
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e31210-e31210
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Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
Author / Creator:Kruschinski, Anna ; Moosmann, Andreas ; Poschke, Isabel ; Norell, Håkan ; Chmielewski, Markus ; Seliger, Barbara ; Kiessling, Rolf ; Blankenstein, Thomas ; Abken, Hinrich ; Charo, Jehad
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (45), p.17481-17486
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Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone
Author / Creator:Krug, Christian ; Birkholz, Katrin ; Paulus, Alexander ; Schwenkert, Michael ; Schmidt, Patrick ; Hoffmann, Nicole ; Hombach, Andreas ; Fey, Georg ; Abken, Hinrich ; Schuler, Gerold ; Schuler-Thurner, Beatrice ; Dörrie, Jan ; Schaft, Niels
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2015-12, Vol.64 (12), p.1623-1635
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Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy
Author / Creator:Paasch, Daniela ; Meyer, Johann ; Stamopoulou, Andriana ; Lenz, Daniela ; Kuehle, Johannes ; Kloos, Doreen ; Buchegger, Theresa ; Holzinger, Astrid ; Falk, Christine S. ; Kloth, Christina ; von Kaisenberg, Constantin S. ; Abken, Hinrich ; Schambach, Axel ; Lachmann, Nico ; Morgan, Michael ; Moritz, Thomas
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-03, Vol.11 (6), p.994
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CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B35 control Epstein-Barr virus-associated lymphoproliferation
Author / Creator:Dragon, Anna Christina ; Zimmermann, Katharina ; Nerreter, Thomas ; Sandfort, Deborah ; Lahrberg, Julia ; Klöß, Stephan ; Kloth, Christina ; Mangare, Caroline ; Bonifacius, Agnes ; Tischer-Zimmermann, Sabine ; Blasczyk, Rainer ; Maecker-Kolhoff, Britta ; Uchanska-Ziegler, Barbara ; Abken, Hinrich ; Schambach, Axel ; Hudecek, Michael ; Eiz-Vesper, Britta
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-10, Vol.8 (2), p.e000736
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A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer
Author / Creator:Hombach, Andreas A. ; Ambrose, Christine ; Lobb, Roy ; Rennert, Paul ; Abken, Hinrich
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-01, Vol.12 (2), p.248
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An Il12-Il2-Antibody Fusion Protein Targeting Hodgkin's Lymphoma Cells Potentiates Activation Of Nk And T Cells For An Anti-Tumor Attack
Author / Creator:Jahn, Tobias ; Zuther, Martin ; Friedrichs, Björn ; Heuser, Claudia ; Guhlke, Stefan ; Abken, Hinrich ; Hombach, Andreas A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e44482-e44482
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CAR Triggered Release of Type-1 Interferon Limits CAR T-Cell Activities by an Artificial Negative Autocrine Loop
Author / Creator:Harrer, Dennis Christoph ; Schenkel, Charlotte ; Bezler, Valerie ; Kaljanac, Marcell ; Hartley, Jordan ; Barden, Markus ; Pan, Hong ; Holzinger, Astrid ; Herr, Wolfgang ; Abken, Hinrich
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3839
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Membrane anchored IL-18 linked to constitutively active TLR4 and CD40 improves human T cell antitumor capacities for adoptive cell therapy
Author / Creator:Blokon-Kogan, Dayana ; Levi-Mann, Maya ; Malka-Levy, Lior ; Itzhaki, Orit ; Besser, Michal J ; Shiftan, Yuval ; Szöőr, Árpád ; Vereb, György ; Gross, Gideon ; Abken, Hinrich ; Weinstein-Marom, Hadas
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-09, Vol.10 (9), p.e001544
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Showing 1 to 20 of 69 results

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CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells

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Nanobody Based Dual Specific CARs

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Weal and woe of interleukin-18 in the T cell therapy of cancer

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Chimeric antigen receptors designed to overcome transforming growth factor‐β‐mediated repression in the adoptive T‐cell therapy of solid tumors

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FimH-based display of functional eukaryotic proteins on bacteria surfaces

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IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells

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Design and Characterization of an “All-in-One” Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines

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Eradication of melanomas by targeted elimination of a minor subset of tumor cells

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Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

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International Regensburg Center for Interventional Immunology (RCI) symposium on “Synthetic immunology and environment-adapted redirection of T cells”, 17–18 July, 2019, Regensburg, Germany

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Chimeric Antigen Receptor (CAR) T Cells Releasing Soluble SLAMF6 Isoform 2 Gain Superior Anti-Cancer Cell Functionality in an Auto-Stimulatory Fashion

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Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection

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Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas

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Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone

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Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy

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CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B35 control Epstein-Barr virus-associated lymphoproliferation

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A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer

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An Il12-Il2-Antibody Fusion Protein Targeting Hodgkin's Lymphoma Cells Potentiates Activation Of Nk And T Cells For An Anti-Tumor Attack

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CAR Triggered Release of Type-1 Interferon Limits CAR T-Cell Activities by an Artificial Negative Autocrine Loop

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Membrane anchored IL-18 linked to constitutively active TLR4 and CD40 improves human T cell antitumor capacities for adoptive cell therapy

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