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Evidence for a Protective Role of Metallothionein-1 in Focal Cerebral Ischemia

Evidence for a Protective Role of Metallothionein-1 in Focal Cerebral Ischemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_96_22_12870

Evidence for a Protective Role of Metallothionein-1 in Focal Cerebral Ischemia

About this item

Full title

Evidence for a Protective Role of Metallothionein-1 in Focal Cerebral Ischemia

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12870-12875

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Metallothioneins (MTs) are a family of metal binding proteins that have been proposed to participate in a cellular defense against zinc toxicity and free radicals. In the present study, we investigated whether increased expression of MT in MT-1 isoform-overexpressing transgenic mice (MT-TG) affords protection against mild focal cerebral ischemia an...

Alternative Titles

Full title

Evidence for a Protective Role of Metallothionein-1 in Focal Cerebral Ischemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_1073_pnas_96_22_12870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1073_pnas_96_22_12870

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.96.22.12870

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