L7 Laquinimod in the R6/2 mouse model of huntington’s disease
L7 Laquinimod in the R6/2 mouse model of huntington’s disease
About this item
Full title
L7 Laquinimod in the R6/2 mouse model of huntington’s disease
Author / Creator
Journal title
Journal of neurology, neurosurgery and psychiatry, 2016-09, Vol.87 (Suppl 1), p.A92-A92
Language
English
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Scope and Contents
Contents
IntroductionThe transgenic mouse model R6/2 (141–157 CAG repeats) of Huntington’s disease (HD) recapitulates basic pathophysiological similarities of HD and some of its clinical symptoms.Laquinimod as an immunomodulatory orally substance has shown to downregulate astrocytic and microglial activation which are common pathways in neurodegenerative di...
Alternative Titles
Full title
L7 Laquinimod in the R6/2 mouse model of huntington’s disease
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Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1136_jnnp_2016_314597_262
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1136_jnnp_2016_314597_262
Other Identifiers
ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp-2016-314597.262
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