L8 Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioura...
L8 Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of huntington’s disease
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English
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BackgroundIncreasing evidence supports a role for abnormal immune activation and inflammatory responses in Huntington’s disease (HD). Aim and methodIn this study, we evaluated the therapeutic potential of laquinimod (1 and 10 mg/kg), a novel immunomodulatory agent shown to be protective in a number of neuroinflammatory conditions, in the YAC128 mou...
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L8 Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of huntington’s disease
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TN_cdi_crossref_primary_10_1136_jnnp_2016_314597_263
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1136_jnnp_2016_314597_263
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0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp-2016-314597.263
