Mechanisms of Targeting the MDM2-p53-FOXM1 Axis in Well-Differentiated Intestinal Neuroendocrine Tum...
Mechanisms of Targeting the MDM2-p53-FOXM1 Axis in Well-Differentiated Intestinal Neuroendocrine Tumors
About this item
Full title
Author / Creator
Briest, Franziska , Grass, Irina , Sedding, Dagmar , Möbs, Markus , Christen, Friederike , Benecke, Joana , Fuchs, Karolin , Mende, Stefanie , Kaemmerer, Daniel , Sänger, Jörg , Kunze, Almut , Geisler, Christina , Freitag, Helma , Lewens, Florentine , Worpenberg, Lina , Iwaszkiewicz, Sara , Siegmund, Britta , Walther, Wolfgang , Hummel, Michael and Grabowski, Patricia
Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publication information
Publisher
Basel, Switzerland: S. Karger AG
Subjects
More information
Scope and Contents
Contents
Background/Aims: The tumor suppressor p53 is rarely mutated in gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) but they frequently show a strong expression of negative regulators of p53, rendering these tumors excellent targets for a p53 recovery therapy. Therefore, we analyzed the mechanisms of a p53 recovery therapy on intestinal neuroe...
Alternative Titles
Full title
Mechanisms of Targeting the MDM2-p53-FOXM1 Axis in Well-Differentiated Intestinal Neuroendocrine Tumors
Authors, Artists and Contributors
Author / Creator
Grass, Irina
Sedding, Dagmar
Möbs, Markus
Christen, Friederike
Benecke, Joana
Fuchs, Karolin
Mende, Stefanie
Kaemmerer, Daniel
Sänger, Jörg
Kunze, Almut
Geisler, Christina
Freitag, Helma
Lewens, Florentine
Worpenberg, Lina
Iwaszkiewicz, Sara
Siegmund, Britta
Walther, Wolfgang
Hummel, Michael
Grabowski, Patricia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_1159_000481506
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1159_000481506
Other Identifiers
ISSN
0028-3835
E-ISSN
1423-0194
DOI
10.1159/000481506
