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Pharmacokinetics and Biodistribution Study of 7A7 Anti-Mouse Epidermal Growth Factor Receptor Monocl...

Pharmacokinetics and Biodistribution Study of 7A7 Anti-Mouse Epidermal Growth Factor Receptor Monocl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_5402_2012_417515

Pharmacokinetics and Biodistribution Study of 7A7 Anti-Mouse Epidermal Growth Factor Receptor Monoclonal Antibody and Its Fragment in an Immunocompetent Mouse Model

About this item

Full title

Pharmacokinetics and Biodistribution Study of 7A7 Anti-Mouse Epidermal Growth Factor Receptor Monoclonal Antibody and Its Fragment in an Immunocompetent Mouse Model

Journal title

ISRN pharmacology, 2012-11, Vol.2012, p.1-8

Language

English

Formats

More information

Scope and Contents

Contents

Immunocompetent mice, Fc receptor
γ
-chain deficient mice (), and molecular tools as F(ab′)
2
bivalent fragments appear as the most suitable biological models to study the mechanisms of the action of anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs).
In vivo
experiments contrasting antitumor effects of whol...

Alternative Titles

Full title

Pharmacokinetics and Biodistribution Study of 7A7 Anti-Mouse Epidermal Growth Factor Receptor Monoclonal Antibody and Its Fragment in an Immunocompetent Mouse Model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_5402_2012_417515

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_5402_2012_417515

Other Identifiers

ISSN

2090-5173

E-ISSN

2090-5173

DOI

10.5402/2012/417515

How to access this item