Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
About this item
Full title
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
Author / Creator
Journal title
eLife, 2023-11, Vol.12
Language
English
Formats
More information
Scope and Contents
Contents
Many bacteria encode multiple toxin–antitoxin (TA) systems targeting separate, but closely related, cellular functions. The toxin of the
Escherichia coli hipBA
system, HipA, is a kinase that inhibits translation via phosphorylation of glutamyl-tRNA synthetase. Enteropathogenic
E. coli
O127:H6 encodes the
hipBA
-like, tripartite TA...
Alternative Titles
Full title
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_crossref_primary_10_7554_eLife_90400_3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_90400_3
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.90400.3
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