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Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly...

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_98348_3

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models

About this item

Full title

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models

Journal title

eLife, 2025-04, Vol.13

Language

English

Formats

More information

Scope and Contents

Contents

The classical diagnosis of Parkinsonism is based on motor symptoms that are the consequence of nigrostriatal pathway dysfunction and reduced dopaminergic output. However, a decade prior to the emergence of motor issues, patients frequently experience non-motor symptoms, such as a reduced sense of smell (hyposmia). The cellular and molecular bases f...

Alternative Titles

Full title

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models

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Primary Identifiers

Record Identifier

TN_cdi_crossref_primary_10_7554_eLife_98348_3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_7554_eLife_98348_3

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.98348.3

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