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Collective cell durotaxis emerges from long-range intercellular force transmission

Collective cell durotaxis emerges from long-range intercellular force transmission

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_csuc_recercat_oai_recercat_cat_2072_272056

Collective cell durotaxis emerges from long-range intercellular force transmission

About this item

Full title

Collective cell durotaxis emerges from long-range intercellular force transmission

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2016-09, Vol.353 (6304), p.1157-1161

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that exhibited durotaxis even if isolated constituent cells did not. This emergent mode of directed collective cell migration applied to a variety of epithelial cell typ...

Alternative Titles

Full title

Collective cell durotaxis emerges from long-range intercellular force transmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_csuc_recercat_oai_recercat_cat_2072_272056

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_csuc_recercat_oai_recercat_cat_2072_272056

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aaf7119

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