Redox driven B12-ligand switch drives CarH photoresponse
Redox driven B12-ligand switch drives CarH photoresponse
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Author / Creator
Poddar, Harshwardhan , Rios-Santacruz, Ronald , Heyes, Derren J. , Shanmugam, Muralidharan , Brookfield, Adam , Johannissen, Linus O. , Levy, Colin W. , Jeffreys, Laura N. , Zhang, Shaowei , Sakuma, Michiyo , Colletier, Jacques-Philippe , Hay, Sam , Schirò, Giorgio , Weik, Martin , Scrutton, Nigel S. and Leys, David
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
CarH is a coenzyme B
12
-dependent photoreceptor involved in regulating carotenoid biosynthesis. How light-triggered cleavage of the B
12
Co-C bond culminates in CarH tetramer dissociation to initiate transcription remains unclear. Here, a series of crystal structures of the CarH B
12
-binding domain after illumination suggest for...
Alternative Titles
Full title
Redox driven B12-ligand switch drives CarH photoresponse
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TN_cdi_doaj_primary_oai_doaj_org_article_001606f7b0874be9a4255441eb03bd98
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_001606f7b0874be9a4255441eb03bd98
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-40817-6