Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neur...
Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In humans, most neurons are born during embryonic development and have to persist throughout the entire lifespan of an individual. Thus, human neurons have to develop elaborate survival strategies to protect against accidental cell death. We set out to decipher the developmental adaptations resulting in neuronal resilience. We demonstrate that, dur...
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Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death
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TN_cdi_doaj_primary_oai_doaj_org_article_00300127c3a54689be6229871e4d6bb2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00300127c3a54689be6229871e4d6bb2
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05340-4
