Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact...
Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In vitro incubation of nanomaterials with plasma offer insights on biological interactions, but cannot fully explain the in vivo fate of nanomaterials. Here, we use a library of polymer nanoparticles to show how physicochemical characteristics influence blood circulation and early distribution. For particles with different diameters, surface hydrop...
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Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
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TN_cdi_doaj_primary_oai_doaj_org_article_00dc4fa9069d4166b50ad9376daec172
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_00dc4fa9069d4166b50ad9376daec172
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00600-w