Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish
Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The process of sperm-egg fusion is critical for successful fertilization, yet the underlying mechanisms that regulate these steps have remained unclear in vertebrates. Here, we show that both mouse and zebrafish DCST1 and DCST2 are necessary in sperm to fertilize the egg, similar to their orthologs SPE-42 and SPE-49 in
C. elegans
and Sneaky i...
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Full title
Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish
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TN_cdi_doaj_primary_oai_doaj_org_article_021deabe3c6143f4a21fa544fdabccc7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_021deabe3c6143f4a21fa544fdabccc7
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03289-w
