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Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherit...

Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_02bc45df39b347a9acf513e55b060a37

Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy

About this item

Full title

Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2023-05, Vol.16 (5)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Modifier genes contribute significantly to our understanding of pathophysiology in human diseases; however, effective approaches to identify modifier genes are still lacking. Here, we aim to develop a rapid F0-based genetic assay in adult zebrafish using the bag3 gene knockout (bag3e2/e2) cardiomyopathy model as a paradigm. First, by utilizing a cl...

Alternative Titles

Full title

Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_02bc45df39b347a9acf513e55b060a37

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_02bc45df39b347a9acf513e55b060a37

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.049427

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