Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherit...
Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy
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Publisher
England: The Company of Biologists Ltd
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Language
English
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England: The Company of Biologists Ltd
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Contents
Modifier genes contribute significantly to our understanding of pathophysiology in human diseases; however, effective approaches to identify modifier genes are still lacking. Here, we aim to develop a rapid F0-based genetic assay in adult zebrafish using the bag3 gene knockout (bag3e2/e2) cardiomyopathy model as a paradigm. First, by utilizing a cl...
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Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_02bc45df39b347a9acf513e55b060a37
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_02bc45df39b347a9acf513e55b060a37
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.049427