Inflammation status modulates the effect of host genetic variation on intestinal gene expression in...
Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
More than 240 genetic risk loci have been associated with inflammatory bowel disease (IBD), but little is known about how they contribute to disease development in involved tissue. Here, we hypothesized that host genetic variation affects gene expression in an inflammation-dependent way, and investigated 299 snap-frozen intestinal biopsies from inf...
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Full title
Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease
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TN_cdi_doaj_primary_oai_doaj_org_article_02cc8b0b815a4d49ba031137f6cb44b3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_02cc8b0b815a4d49ba031137f6cb44b3
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21458-z
