Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
About this item
Full title
Author / Creator
Louet, Maxime , Casiraghi, Marina , Damian, Marjorie , Costa, Mauricio GS , Renault, Pedro , Gomes, Antoniel AS , Batista, Paulo R , M'Kadmi, Céline , Mary, Sophie , Cantel, Sonia , Denoyelle, Severine , Ben Haj Salah, Khoubaib , Perahia, David , Bisch, Paulo M , Fehrentz, Jean-Alain , Catoire, Laurent J , Floquet, Nicolas and Banères, Jean-Louis
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Sciences Publications Ltd
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More information
Scope and Contents
Contents
There is increasing support for water molecules playing a role in signal propagation through G protein-coupled receptors (GPCRs). However, exploration of the hydration features of GPCRs is still in its infancy. Here, we combined site-specific labeling with unnatural amino acids to molecular dynamics to delineate how local hydration of the ghrelin r...
Alternative Titles
Full title
Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
Authors, Artists and Contributors
Author / Creator
Casiraghi, Marina
Damian, Marjorie
Costa, Mauricio GS
Renault, Pedro
Gomes, Antoniel AS
Batista, Paulo R
M'Kadmi, Céline
Mary, Sophie
Cantel, Sonia
Denoyelle, Severine
Ben Haj Salah, Khoubaib
Perahia, David
Bisch, Paulo M
Fehrentz, Jean-Alain
Catoire, Laurent J
Floquet, Nicolas
Banères, Jean-Louis
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0314baab73134fab94c1e7b73579cdc2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0314baab73134fab94c1e7b73579cdc2
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.63201
