Zika virus vertical transmission in interferon receptor1-antagonized Rag1 -/- mice results in postna...
Zika virus vertical transmission in interferon receptor1-antagonized Rag1 -/- mice results in postnatal brain abnormalities and clinical disease
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The mechanisms by which vertically transmitted Zika virus (ZIKV) causes postnatal brain development abnormalities and congenital disease remain poorly understood. Here, we optimized the established anti-IFNAR1 treated, Rag1
(AIR) mouse model of ZIKV infection to examine the consequence of vertical transmission on neonate survival and postnatal b...
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Zika virus vertical transmission in interferon receptor1-antagonized Rag1 -/- mice results in postnatal brain abnormalities and clinical disease
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TN_cdi_doaj_primary_oai_doaj_org_article_037a6072fc4c4ab7b4c7b21e7d1e4d7c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_037a6072fc4c4ab7b4c7b21e7d1e4d7c
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-022-01351-6
