Capture Hi-C identifies putative target genes at 33 breast cancer risk loci
Capture Hi-C identifies putative target genes at 33 breast cancer risk loci
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Author / Creator
Baxter, Joseph S. , Leavy, Olivia C. , Dryden, Nicola H. , Maguire, Sarah , Johnson, Nichola , Fedele, Vita , Simigdala, Nikiana , Martin, Lesley-Ann , Andrews, Simon , Wingett, Steven W. , Assiotis, Ioannis , Fenwick, Kerry , Chauhan, Ritika , Rust, Alistair G. , Orr, Nick , Dudbridge, Frank , Haider, Syed and Fletcher, Olivia
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Genome-wide association studies (GWAS) have identified approximately 100 breast cancer risk loci. Translating these findings into a greater understanding of the mechanisms that influence disease risk requires identification of the genes or non-coding RNAs that mediate these associations. Here, we use Capture Hi-C (CHi-C) to annotate 63 loci; we ide...
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Full title
Capture Hi-C identifies putative target genes at 33 breast cancer risk loci
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TN_cdi_doaj_primary_oai_doaj_org_article_04f38edcab7d46faa2e61354e4ef0a11
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_04f38edcab7d46faa2e61354e4ef0a11
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03411-9
