Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria...
Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria vaccine trials?
About this item
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Early phase malaria vaccine field trials typically measure malaria infection by PCR or thick blood smear microscopy performed on serially sampled blood. Vaccine efficacy (VE) is the proportion reduction in an endpoint due to vaccination and is often calculated as VE
= 1-hazard ratio or VE
= 1-risk ratio. Genotyping information can distingui...
Alternative Titles
Full title
Can incorporating genotyping data into efficacy estimators improve efficiency of early phase malaria vaccine trials?
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_053e346859e2446086ce6e39b53fa97f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_053e346859e2446086ce6e39b53fa97f
Other Identifiers
ISSN
1475-2875
E-ISSN
1475-2875
DOI
10.1186/s12936-023-04802-0
