The genetic regulatory signature of type 2 diabetes in human skeletal muscle
The genetic regulatory signature of type 2 diabetes in human skeletal muscle
About this item
Full title
Author / Creator
Scott, Laura J. , Erdos, Michael R. , Huyghe, Jeroen R. , Welch, Ryan P. , Beck, Andrew T. , Wolford, Brooke N. , Chines, Peter S. , Didion, John P. , Narisu, Narisu , Stringham, Heather M. , Taylor, D. Leland , Jackson, Anne U. , Vadlamudi, Swarooparani , Bonnycastle, Lori L. , Kinnunen, Leena , Saramies, Jouko , Sundvall, Jouko , Albanus, Ricardo D'Oliveira , Kiseleva, Anna , Hensley, John , Crawford, Gregory E. , Jiang, Hui , Wen, Xiaoquan , Watanabe, Richard M. , Lakka, Timo A. , Mohlke, Karen L. , Laakso, Markku , Tuomilehto, Jaakko , Koistinen, Heikki A. , Boehnke, Michael , Collins, Francis S. and Parker, Stephen C. J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Type 2 diabetes (T2D) results from the combined effects of genetic and environmental factors on multiple tissues over time. Of the >100 variants associated with T2D and related traits in genome-wide association studies (GWAS), >90% occur in non-coding regions, suggesting a strong regulatory component to T2D risk. Here to understand how T2D status,...
Alternative Titles
Full title
The genetic regulatory signature of type 2 diabetes in human skeletal muscle
Authors, Artists and Contributors
Author / Creator
Erdos, Michael R.
Huyghe, Jeroen R.
Welch, Ryan P.
Beck, Andrew T.
Wolford, Brooke N.
Chines, Peter S.
Didion, John P.
Narisu, Narisu
Stringham, Heather M.
Taylor, D. Leland
Jackson, Anne U.
Vadlamudi, Swarooparani
Bonnycastle, Lori L.
Kinnunen, Leena
Saramies, Jouko
Sundvall, Jouko
Albanus, Ricardo D'Oliveira
Kiseleva, Anna
Hensley, John
Crawford, Gregory E.
Jiang, Hui
Wen, Xiaoquan
Watanabe, Richard M.
Lakka, Timo A.
Mohlke, Karen L.
Laakso, Markku
Tuomilehto, Jaakko
Koistinen, Heikki A.
Boehnke, Michael
Collins, Francis S.
Parker, Stephen C. J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_05b203e73f38446db6c6345b6a617738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_05b203e73f38446db6c6345b6a617738
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11764
