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Mohlke, Karen L
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: MEL-OCK, 2022, p.7898-7898
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Mohlke, Karen L
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: MEN-OFT, 2021, p.7873-7873
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A map of open chromatin in human pancreatic islets
Author / Creator:Gaulton, Kyle J ; Nammo, Takao ; Pasquali, Lorenzo ; Simon, Jeremy M ; Giresi, Paul G ; Fogarty, Marie P ; Panhuis, Tami M ; Mieczkowski, Piotr ; Secchi, Antonio ; Bosco, Domenico ; Berney, Thierry ; Montanya, Eduard ; Mohlke, Karen L ; Lieb, Jason D ; Ferrer, Jorge
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2010-03, Vol.42 (3), p.255-259
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The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance
Author / Creator:Miao, Zong ; Alvarez, Marcus ; Ko, Arthur ; Bhagat, Yash ; Rahmani, Elior ; Jew, Brandon ; Heinonen, Sini ; Muñoz-Hernandez, Linda Liliana ; Herrera-Hernandez, Miguel ; Aguilar-Salinas, Carlos ; Tusie-Luna, Teresa ; Mohlke, Karen L. ; Laakso, Markku ; Pietiläinen, Kirsi H. ; Halperin, Eran ; Pajukanta, Päivi
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2020-09, Vol.16 (9), p.e1009018
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Pla2g12b drives expansion of triglyceride-rich lipoproteins
Author / Creator:Thierer, James H. ; Foresti, Ombretta ; Yadav, Pradeep Kumar ; Wilson, Meredith H. ; Moll, Tabea O. C. ; Shen, Meng-Chieh ; Busch-Nentwich, Elisabeth M. ; Morash, Margaret ; Mohlke, Karen L. ; Rawls, John F. ; Malhotra, Vivek ; Hussain, M. Mahmood ; Farber, Steven A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-03, Vol.15 (1), p.2095-17, Article 2095
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Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
Author / Creator:Huyghe, Jeroen R ; Jackson, Anne U ; Fogarty, Marie P ; Buchkovich, Martin L ; Stančáková, Alena ; Stringham, Heather M ; Sim, Xueling ; Yang, Lingyao ; Fuchsberger, Christian ; Cederberg, Henna ; Chines, Peter S ; Teslovich, Tanya M ; Romm, Jane M ; Ling, Hua ; McMullen, Ivy ; Ingersoll, Roxann ; Pugh, Elizabeth W ; Doheny, Kimberly F ; Neale, Benjamin M ; Daly, Mark J ; Kuusisto, Johanna ; Scott, Laura J ; Kang, Hyun Min ; Collins, Francis S ; Abecasis, Gonçalo R ; Watanabe, Richard M ; Boehnke, Michael ; Laakso, Markku ; Mohlke, Karen L
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-02, Vol.45 (2), p.197-201
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Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci
Author / Creator:Perrin, Hannah J. ; Currin, Kevin W. ; Vadlamudi, Swarooparani ; Pandey, Gautam K. ; Ng, Kenneth K. ; Wabitsch, Martin ; Laakso, Markku ; Love, Michael I. ; Mohlke, Karen L.
Publisher:San Francisco: Public Library of Science
Journal title:PLoS genetics, 2021-10, Vol.17 (10), p.e1009865-e1009865
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Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS
Author / Creator:Pan, David Z. ; Garske, Kristina M. ; Alvarez, Marcus ; Bhagat, Yash V. ; Boocock, James ; Nikkola, Elina ; Miao, Zong ; Raulerson, Chelsea K. ; Cantor, Rita M. ; Civelek, Mete ; Glastonbury, Craig A. ; Small, Kerrin S. ; Boehnke, Michael ; Lusis, Aldons J. ; Sinsheimer, Janet S. ; Mohlke, Karen L. ; Laakso, Markku ; Pajukanta, Päivi ; Ko, Arthur
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-04, Vol.9 (1), p.1512-11, Article 1512
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Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus
Author / Creator:Fogarty, Marie P. ; Cannon, Maren E. ; Vadlamudi, Swarooparani ; Gaulton, Kyle J. ; Mohlke, Karen L.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2014-09, Vol.10 (9), p.e1004633
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The genetic regulatory signature of type 2 diabetes in human skeletal muscle
Author / Creator:Scott, Laura J. ; Erdos, Michael R. ; Huyghe, Jeroen R. ; Welch, Ryan P. ; Beck, Andrew T. ; Wolford, Brooke N. ; Chines, Peter S. ; Didion, John P. ; Narisu, Narisu ; Stringham, Heather M. ; Taylor, D. Leland ; Jackson, Anne U. ; Vadlamudi, Swarooparani ; Bonnycastle, Lori L. ; Kinnunen, Leena ; Saramies, Jouko ; Sundvall, Jouko ; Albanus, Ricardo D'Oliveira ; Kiseleva, Anna ; Hensley, John ; Crawford, Gregory E. ; Jiang, Hui ; Wen, Xiaoquan ; Watanabe, Richard M. ; Lakka, Timo A. ; Mohlke, Karen L. ; Laakso, Markku ; Tuomilehto, Jaakko ; Koistinen, Heikki A. ; Boehnke, Michael ; Collins, Francis S. ; Parker, Stephen C. J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-06, Vol.7 (1), p.11764-12, Article 11764
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Publisher Correction: Pla2g12b drives expansion of triglyceride-rich lipoproteins
Author / Creator:Thierer, James H. ; Foresti, Ombretta ; Yadav, Pradeep Kumar ; Wilson, Meredith H. ; Moll, Tabea O. C. ; Shen, Meng-Chieh ; Busch-Nentwich, Elisabeth M. ; Morash, Margaret ; Mohlke, Karen L. ; Rawls, John F. ; Malhotra, Vivek ; Hussain, M. Mahmood ; Farber, Steven A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-03, Vol.15 (1), p.2572-2572, Article 2572
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ArticlesPeer ReviewedFull Text
INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis
Author / Creator:Liu, Yan ; Sanoff, Hanna K. ; Cho, Hyunsoon ; Burd, Christin E. ; Torrice, Chad ; Mohlke, Karen L. ; Ibrahim, Joseph G. ; Thomas, Nancy E. ; Sharpless, Norman E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-04, Vol.4 (4), p.e5027-e5027
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Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey
Author / Creator:Spracklen, Cassandra N. ; Shi, Jinxiu ; Vadlamudi, Swarooparani ; Wu, Ying ; Zou, Meng ; Raulerson, Chelsea K. ; Davis, James P. ; Zeynalzadeh, Monica ; Jackson, Kayla ; Yuan, Wentao ; Wang, Haifeng ; Shou, Weihua ; Wang, Ying ; Luo, Jingchun ; Lange, Leslie A. ; Lange, Ethan M. ; Popkin, Barry M. ; Gordon-Larsen, Penny ; Du, Shufa ; Huang, Wei ; Mohlke, Karen L.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2018-04, Vol.14 (4), p.e1007275-e1007275
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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
Author / Creator:Davis, James P. ; Huyghe, Jeroen R. ; Locke, Adam E. ; Jackson, Anne U. ; Sim, Xueling ; Stringham, Heather M. ; Teslovich, Tanya M. ; Welch, Ryan P. ; Fuchsberger, Christian ; Narisu, Narisu ; Chines, Peter S. ; Kangas, Antti J. ; Soininen, Pasi ; Ala-Korpela, Mika ; Kuusisto, Johanna ; Collins, Francis S. ; Laakso, Markku ; Boehnke, Michael ; Mohlke, Karen L.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2017-10, Vol.13 (10), p.e1007079-e1007079
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Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions
Author / Creator:Kar, Asha ; Alvarez, Marcus ; Garske, Kristina M. ; Huang, Huiling ; Lee, Seung Hyuk T. ; Deal, Milena ; Das, Sankha Subhra ; Koka, Amogha ; Jamal, Zoeb ; Mohlke, Karen L. ; Laakso, Markku ; Heinonen, Sini ; Pietiläinen, Kirsi H. ; Pajukanta, Päivi
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2024-01, Vol.16 (1), p.19-24, Article 19
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Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes
Author / Creator:Pan, David Z. ; Miao, Zong ; Comenho, Caroline ; Rajkumar, Sandhya ; Koka, Amogha ; Lee, Seung Hyuk T. ; Alvarez, Marcus ; Kaminska, Dorota ; Ko, Arthur ; Sinsheimer, Janet S. ; Mohlke, Karen L. ; Mancuso, Nicholas ; Muñoz-Hernandez, Linda Liliana ; Herrera-Hernandez, Miguel ; Tusié-Luna, Maria Teresa ; Aguilar-Salinas, Carlos ; Pietiläinen, Kirsi H. ; Pihlajamäki, Jussi ; Laakso, Markku ; Garske, Kristina M. ; Pajukanta, Päivi
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2021-08, Vol.13 (1), p.123-123, Article 123
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Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences
Author / Creator:Spracklen, Cassandra N. ; Iyengar, Apoorva K. ; Vadlamudi, Swarooparani ; Raulerson, Chelsea K. ; Jackson, Anne U. ; Brotman, Sarah M. ; Wu, Ying ; Cannon, Maren E. ; Davis, James P. ; Crain, Aaron T. ; Currin, Kevin W. ; Perrin, Hannah J. ; Narisu, Narisu ; Stringham, Heather M. ; Fuchsberger, Christian ; Locke, Adam E. ; Welch, Ryan P. ; Kuusisto, Johanna K. ; Pajukanta, Päivi ; Scott, Laura J. ; Li, Yun ; Collins, Francis S. ; Boehnke, Michael ; Laakso, Markku ; Mohlke, Karen L.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2020-09, Vol.16 (9), p.e1009019
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Allele-Specific Transcriptional Activity at Type 2 Diabetes–Associated Single Nucleotide Polymorphisms in Regions of Pancreatic Islet Open Chromatin at the JAZF1 Locus
Author / Creator:Fogarty, Marie P. ; Panhuis, Tami M. ; Vadlamudi, Swarooparani ; Buchkovich, Martin L. ; Mohlke, Karen L.
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-05, Vol.62 (5), p.1756-1762
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Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits
Author / Creator:Cannon, Maren E ; Currin, Kevin W ; Young, Kristin L ; Perrin, Hannah J ; Vadlamudi, Swarooparani ; Safi, Alexias ; Song, Lingyun ; Wu, Ying ; Wabitsch, Martin ; Laakso, Markku ; Crawford, Gregory E ; Mohlke, Karen L
Publisher:Oxford: Oxford University Press
Journal title:G3 : genes - genomes - genetics, 2019-08, Vol.9 (8), p.2521-2533
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Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample
Author / Creator:Scott, Laura J. ; Bonnycastle, Lori L. ; Willer, Cristen J. ; Sprau, Andrew G. ; Jackson, Anne U. ; Narisu, Narisu ; Duren, William L. ; Chines, Peter S. ; Stringham, Heather M. ; Erdos, Michael R. ; Valle, Timo T. ; Tuomilehto, Jaakko ; Bergman, Richard N. ; Mohlke, Karen L. ; Collins, Francis S. ; Boehnke, Michael
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2006-09, Vol.55 (9), p.2649-2653
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Mohlke, Karen L

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Mohlke, Karen L

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A map of open chromatin in human pancreatic islets

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The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance

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Pla2g12b drives expansion of triglyceride-rich lipoproteins

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Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

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Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci

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Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

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Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus

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The genetic regulatory signature of type 2 diabetes in human skeletal muscle

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Publisher Correction: Pla2g12b drives expansion of triglyceride-rich lipoproteins

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INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis

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Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey

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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

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Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions

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Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

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Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

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Allele-Specific Transcriptional Activity at Type 2 Diabetes–Associated Single Nucleotide Polymorphisms in Regions of Pancreatic Islet Open Chromatin at the JAZF1 Locus

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Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

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Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample

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