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Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06210cd3488c496e91580c92cd6a7e1e

Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

About this item

Full title

Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2024-08, Vol.15 (8), p.585-12, Article 585

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Sulfur mustard (SM) is a highly toxic chemical warfare agent. Exposure to SM results in various pathologies including skin lesions with subsequent impaired wound healing. To date, there are no effective treatments available. Here we discover a SM-triggered pathomechanism involving miR-497-5p and its target survivin which contributes to keratinocyte...

Alternative Titles

Full title

Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_06210cd3488c496e91580c92cd6a7e1e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06210cd3488c496e91580c92cd6a7e1e

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-024-06974-2

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