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ArticlesPeer ReviewedFull Text
Organophosphorus compounds and oximes: a critical review
Author / Creator:Worek, Franz ; Thiermann, Horst ; Wille, Timo
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2020-07, Vol.94 (7), p.2275-2292
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Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative d...
Author / Creator:Tigges, Jonas ; Worek, Franz ; Thiermann, Horst ; Wille, Timo
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2022-01, Vol.96 (1), p.321-334
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Recombinant cellular model system for human muscle-type nicotinic acetylcholine receptor α1₂β1δε
Author / Creator:Brockmöller, Sabrina ; Seeger, Thomas ; Worek, Franz ; Rothmiller, Simone
Publisher:Dordrecht: Springer Science + Business Media
Journal title:Cell stress & chaperones, 2023-11, Vol.28 (6), p.1013-1025
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Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro
Author / Creator:Köhler, Anja ; Escher, Benjamin ; Job, Laura ; Koller, Marianne ; Thiermann, Horst ; Skerra, Arne ; Worek, Franz
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2021-08, Vol.95 (8), p.2815-2823
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In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase
Author / Creator:Worek, Franz ; Thiermann, Horst ; Koller, Marianne ; Wille, Timo
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-07, Vol.25 (13), p.3029
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Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model
Author / Creator:Wagner, Sylvia ; Zensi, Anja ; Wien, Sascha L. ; Tschickardt, Sabrina E. ; Maier, Wladislaw ; Vogel, Tikva ; Worek, Franz ; Pietrzik, Claus U. ; Kreuter, Jörg ; von Briesen, Hagen
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e32568
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Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo
Author / Creator:Kranawetvogl, Tamara ; Kranawetvogl, Andreas ; Scheidegger, Lisa ; Wille, Timo ; Steinritz, Dirk ; Worek, Franz ; Thiermann, Horst ; John, Harald
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2023-07, Vol.97 (7), p.1873-1885
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Post-VX exposure treatment of rats with engineered phosphotriesterases
Author / Creator:Stigler, Lisa ; Köhler, Anja ; Koller, Marianne ; Job, Laura ; Escher, Benjamin ; Potschka, Heidrun ; Thiermann, Horst ; Skerra, Arne ; Worek, Franz ; Wille, Timo
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2022-02, Vol.96 (2), p.571-583
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Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin
Author / Creator:Kranawetvogl, Andreas ; Küppers, Jim ; Siegert, Markus ; Gütschow, Michael ; Worek, Franz ; Thiermann, Horst ; Elsinghorst, Paul W. ; John, Harald
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2018-02, Vol.410 (5), p.1463-1474
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Cell-Sonar, a Novel Method for Intracellular Tracking of Secretory Pathways
Author / Creator:Brockmöller, Sabrina ; Seeger, Thomas ; Worek, Franz ; Rothmiller, Simone
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-08, Vol.13 (17), p.1449
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Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard
Author / Creator:Egea, Virginia ; Lutterberg, Karina ; Steinritz, Dirk ; Rothmiller, Simone ; Steinestel, Konrad ; Caca, Jan ; Nerlich, Andreas ; Blum, Helmut ; Reschke, Sarah ; Khani, Sajjad ; Bartelt, Alexander ; Worek, Franz ; Thiermann, Horst ; Weber, Christian ; Ries, Christian
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2024-08, Vol.15 (8), p.585-12, Article 585
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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
Author / Creator:Gorecki, Lukas ; Hepnarova, Vendula ; Karasova, Jana Zdarova ; Hrabinova, Martina ; Courageux, Charlotte ; Dias, José ; Kucera, Tomas ; Kobrlova, Tereza ; Muckova, Lubica ; Prchal, Lukas ; Malinak, David ; Jun, Daniel ; Musilek, Kamil ; Worek, Franz ; Nachon, Florian ; Soukup, Ondrej ; Korabecny, Jan
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2021-03, Vol.95 (3), p.985-1001
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V-type nerve agents phosphonylate ubiquitin at biologically relevant lysine residues and induce intramolecular cyclization by an isopeptide bond
Author / Creator:Schmidt, Christian ; Breyer, Felicitas ; Blum, Marc-Michael ; Thiermann, Horst ; Worek, Franz ; John, Harald
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2014-08, Vol.406 (21), p.5171-5185
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ArticlesPeer ReviewedFull Text
Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial
Author / Creator:Eddleston, Michael ; Eyer, Peter ; Worek, Franz ; Juszczak, Edmund ; Alder, Nicola ; Mohamed, Fahim ; Senarathna, Lalith ; Hittarage, Ariyasena ; Azher, Shifa ; Jeganathan, K. ; Jayamanne, Shaluka ; von Meyer, Ludwig ; Dawson, Andrew H. ; Sheriff, Mohamed Hussain Rezvi ; Buckley, Nick A.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2009-06, Vol.6 (6), p.e1000104
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ArticlesPeer ReviewedFull Text
Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model
Author / Creator:Wagner, Sylvia ; Kufleitner, Jürgen ; Zensi, Anja ; Dadparvar, Miriam ; Wien, Sascha ; Bungert, Judith ; Vogel, Tikva ; Worek, Franz ; Kreuter, Jörg ; von Briesen, Hagen
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-12, Vol.5 (12), p.e14213
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ArticlesPeer ReviewedFull Text
Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines
Author / Creator:Ring, Avi ; Strom, Bjorn Oddvar ; Turner, Simon R. ; Timperley, Christopher M. ; Bird, Michael ; Green, A. Christopher ; Chad, John E. ; Worek, Franz ; Tattersall, John E. H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-08, Vol.10 (8), p.e0135811
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Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study
Author / Creator:Eddleston, Michael ; Eyer, Peter ; Worek, Franz ; Mohamed, Fahim ; Senarathna, Lalith ; von Meyer, Ludwig ; Juszczak, Edmund ; Hittarage, Ariyasena ; Azhar, Shifa ; Dissanayake, Wasantha ; Sheriff, MH Rezvi ; Szinicz, Ladislaus ; Dawson, Andrew H ; Buckley, Nick A
Publisher:London: Elsevier Ltd
Journal title:The Lancet (British edition), 2005-10, Vol.366 (9495), p.1452-1459
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An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
Author / Creator:Allgardsson, Anders ; David Andersson, C. ; Akfur, Christine ; Worek, Franz ; Linusson, Anna ; Ekström, Fredrik
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2017-08, Vol.22 (9), p.1433
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ArticlesPeer ReviewedFull Text
Toxicology of organophosphorus compounds in view of an increasing terrorist threat
Author / Creator:Worek, Franz ; Wille, Timo ; Koller, Marianne ; Thiermann, Horst
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2016-09, Vol.90 (9), p.2131-2145
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ArticlesPeer ReviewedFull Text
Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts
Author / Creator:John, Harald ; Koller, Marianne ; Worek, Franz ; Thiermann, Horst ; Siegert, Markus
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Archives of toxicology, 2019-07, Vol.93 (7), p.1881-1891
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Showing 1 to 20 of 44 results

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Organophosphorus compounds and oximes: a critical review

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Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative d...

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Recombinant cellular model system for human muscle-type nicotinic acetylcholine receptor α1₂β1δε

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Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro

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In Vitro Interaction of Organophosphono- and Organophosphorothioates with Human Acetylcholinesterase

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Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model

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Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

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Post-VX exposure treatment of rats with engineered phosphotriesterases

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Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin

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Cell-Sonar, a Novel Method for Intracellular Tracking of Secretory Pathways

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Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase

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V-type nerve agents phosphonylate ubiquitin at biologically relevant lysine residues and induce intramolecular cyclization by an isopeptide bond

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Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial

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Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model

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Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines

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Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study

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An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet

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Toxicology of organophosphorus compounds in view of an increasing terrorist threat

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Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts

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