Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
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McDonald, J. Tyson , Kim, JangKeun , Farmerie, Lily , Johnson, Meghan L. , Trovao, Nidia S. , Arif, Shehbeel , Siew, Keith , Tsoy, Sergey , Bram, Yaron , Park, Jiwoon , Overbey, Eliah , Ryon, Krista , Haltom, Jeffrey , Singh, Urminder , Enguita, Francisco J. , Zaksas, Victoria , Guarnieri, Joseph W. , Topper, Michael , Wallace, Douglas C. , Meydan, Cem , Baylin, Stephen , Meller, Robert , Muratani, Masafumi , Porterfield, D. Marshall , Kaufman, Brett , Mori, Marcelo A. , Walsh, Stephen B. , Sigaudo-Roussel, Dominique , Mebarek, Saida , Bottini, Massimo , Marquette, Christophe A. , Wurtele, Eve Syrkin , Schwartz, Robert E. , Galeano, Diego , Mason, Christopher E. , Grabham, Peter and Beheshti, Afshin
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London: Springer Nature
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English
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London: Springer Nature
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© The Author(s) 2024. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Our previous research revealed a key microRNA signature that is associated with spaceflight that can be used as a biomarker and to develop countermeasure treatments to mitigate the damage caused by space radiation. Here, we expand on this work to determine the biological factors rescued by the countermeasure treatment. We performed RNA-seq...
Alternative Titles
Full title
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs
Authors, Artists and Contributors
Author / Creator
Kim, JangKeun
Farmerie, Lily
Johnson, Meghan L.
Trovao, Nidia S.
Arif, Shehbeel
Siew, Keith
Tsoy, Sergey
Bram, Yaron
Park, Jiwoon
Overbey, Eliah
Ryon, Krista
Haltom, Jeffrey
Singh, Urminder
Enguita, Francisco J.
Zaksas, Victoria
Guarnieri, Joseph W.
Topper, Michael
Wallace, Douglas C.
Meydan, Cem
Baylin, Stephen
Meller, Robert
Muratani, Masafumi
Porterfield, D. Marshall
Kaufman, Brett
Mori, Marcelo A.
Walsh, Stephen B.
Sigaudo-Roussel, Dominique
Mebarek, Saida
Bottini, Massimo
Marquette, Christophe A.
Wurtele, Eve Syrkin
Schwartz, Robert E.
Galeano, Diego
Mason, Christopher E.
Grabham, Peter
Beheshti, Afshin
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0649faa161fd46558b42240dde0a9327
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0649faa161fd46558b42240dde0a9327
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48920-y