Lgr5+ telocytes are a signaling source at the intestinal villus tip
Lgr5+ telocytes are a signaling source at the intestinal villus tip
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Author / Creator
Bahar Halpern, Keren , Massalha, Hassan , Zwick, Rachel K. , Moor, Andreas E. , Castillo-Azofeifa, David , Rozenberg, Milena , Farack, Lydia , Egozi, Adi , Miller, Dan R. , Averbukh, Inna , Harnik, Yotam , Weinberg-Corem, Noa , de Sauvage, Frederic J. , Amit, Ido , Klein, Ophir D. , Shoshkes-Carmel, Michal and Itzkovitz, Shalev
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The intestinal epithelium is a structured organ composed of crypts harboring Lgr5+ stem cells, and villi harboring differentiated cells. Spatial transcriptomics have demonstrated profound zonation of epithelial gene expression along the villus axis, but the mechanisms shaping this spatial variability are unknown. Here, we combine laser capture micr...
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Full title
Lgr5+ telocytes are a signaling source at the intestinal villus tip
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TN_cdi_doaj_primary_oai_doaj_org_article_06a4059134d14359ba2c09cd1b2ad006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06a4059134d14359ba2c09cd1b2ad006
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15714-x
