KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and tram...
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma
About this item
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Author / Creator
Ferrucci, Pier Francesco , Di Giacomo, Anna Maria , Del Vecchio, Michele , Atkinson, Victoria , Schmidt, Henrik , Schachter, Jacob , Queirolo, Paola , Long, Georgina V , Stephens, Rosalie , Svane, Inge Marie , Lotem, Michal , Abu-Amna, Mahmoud , Gasal, Eduard , Ghori, Razi , Diede, Scott J , Croydon, Elizabeth S , Ribas, Antoni , Ascierto, Paolo Antonio and KEYNOTE-022 international team
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd
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Scope and Contents
Contents
BackgroundIn the KEYNOTE-022 study, pembrolizumab with dabrafenib and trametinib (triplet) improved progression-free survival (PFS) versus placebo with dabrafenib and trametinib (doublet) without reaching statistical significance. Mature results on PFS, duration of response (DOR), and overall survival (OS) are reported.MethodsThe double-blind, phas...
Alternative Titles
Full title
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma
Authors, Artists and Contributors
Author / Creator
Di Giacomo, Anna Maria
Del Vecchio, Michele
Atkinson, Victoria
Schmidt, Henrik
Schachter, Jacob
Queirolo, Paola
Long, Georgina V
Stephens, Rosalie
Svane, Inge Marie
Lotem, Michal
Abu-Amna, Mahmoud
Gasal, Eduard
Ghori, Razi
Diede, Scott J
Croydon, Elizabeth S
Ribas, Antoni
Ascierto, Paolo Antonio
KEYNOTE-022 international team
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_06d6c0dbe8904dc09538e628a3bd82da
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_06d6c0dbe8904dc09538e628a3bd82da
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001806