CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast canc...
CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer
About this item
Full title
Author / Creator
Racioppi, Luigi , Nelson, Erik R. , Huang, Wei , Mukherjee, Debarati , Lawrence, Scott A. , Lento, William , Masci, Anna Maria , Jiao, Yiquin , Park, Sunghee , York, Brian , Liu, Yaping , Baek, Amy E. , Drewry, David H. , Zuercher, William J. , Bertani, Francesca R. , Businaro, Luca , Geradts, Joseph , Hall, Allison , Means, Anthony R. , Chao, Nelson , Chang, Ching-yi and McDonnell, Donald P.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tumor-associated myeloid cells regulate tumor growth and metastasis, and their accumulation is a negative prognostic factor for breast cancer. Here we find calcium/calmodulin-dependent kinase kinase (CaMKK2) to be highly expressed within intratumoral myeloid cells in mouse models of breast cancer, and demonstrate that its inhibition within myeloid...
Alternative Titles
Full title
CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer
Authors, Artists and Contributors
Author / Creator
Nelson, Erik R.
Huang, Wei
Mukherjee, Debarati
Lawrence, Scott A.
Lento, William
Masci, Anna Maria
Jiao, Yiquin
Park, Sunghee
York, Brian
Liu, Yaping
Baek, Amy E.
Drewry, David H.
Zuercher, William J.
Bertani, Francesca R.
Businaro, Luca
Geradts, Joseph
Hall, Allison
Means, Anthony R.
Chao, Nelson
Chang, Ching-yi
McDonnell, Donald P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_072c9c0330034d37ac61bcbbffebcda1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_072c9c0330034d37ac61bcbbffebcda1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10424-5
