Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic m...
Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse
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Author / Creator
Muroňová, Jana , Kherraf, Zine Eddine , Giordani, Elsa , Lambert, Emeline , Eckert, Simon , Cazin, Caroline , Amiri-Yekta, Amir , Court, Magali , Chevalier, Geneviève , Martinez, Guillaume , Neirijnck, Yasmine , Kühne, Francoise , Wehrli, Lydia , Klena, Nikolai , Hamel, Virginie , De Macedo, Lisa , Escoffier, Jessica , Guichard, Paul , Coutton, Charles , Mustapha, Selima Fourati Ben , Kharouf, Mahmoud , Bouin, Anne-Pacale , Zouari, Raoudha , Thierry-Mieg, Nicolas , Nef, Serge , Geimer, Stefan , Loeuillet, Corinne , Ray, Pierre F and Arnoult, Christophe
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Sciences Publications Ltd
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More information
Scope and Contents
Contents
From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the
gene. In somatic cells, CCDC146 is located at the centrosome and at multiple microtubule-related organelles during mitotic division, suggesting that it is a microtubule-associ...
Alternative Titles
Full title
Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse
Authors, Artists and Contributors
Author / Creator
Kherraf, Zine Eddine
Giordani, Elsa
Lambert, Emeline
Eckert, Simon
Cazin, Caroline
Amiri-Yekta, Amir
Court, Magali
Chevalier, Geneviève
Martinez, Guillaume
Neirijnck, Yasmine
Kühne, Francoise
Wehrli, Lydia
Klena, Nikolai
Hamel, Virginie
De Macedo, Lisa
Escoffier, Jessica
Guichard, Paul
Coutton, Charles
Mustapha, Selima Fourati Ben
Kharouf, Mahmoud
Bouin, Anne-Pacale
Zouari, Raoudha
Thierry-Mieg, Nicolas
Nef, Serge
Geimer, Stefan
Loeuillet, Corinne
Ray, Pierre F
Arnoult, Christophe
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_078af173188c4adb858332ae057a3a05
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_078af173188c4adb858332ae057a3a05
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.86845
