Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regul...
Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL
About this item
Full title
Author / Creator
Wierzbinska, Justyna A , Toth, Reka , Ishaque, Naveed , Rippe, Karsten , Mallm, Jan-Philipp , Klett, Lara C , Mertens, Daniel , Zenz, Thorsten , Hielscher, Thomas , Seifert, Marc , Küppers, Ralf , Assenov, Yassen , Lutsik, Pavlo , Stilgenbauer, Stephan , Roessner, Philipp M , Seiffert, Martina , Byrd, John , Oakes, Christopher C , Plass, Christoph and Lipka, Daniel B
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
In cancer, normal epigenetic patterns are disturbed and contribute to gene expression changes, disease onset, and progression. The cancer epigenome is composed of the epigenetic patterns present in the tumor-initiating cell at the time of transformation, and the tumor-specific epigenetic alterations that are acquired during tumor initiation and pro...
Alternative Titles
Full title
Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL
Authors, Artists and Contributors
Author / Creator
Toth, Reka
Ishaque, Naveed
Rippe, Karsten
Mallm, Jan-Philipp
Klett, Lara C
Mertens, Daniel
Zenz, Thorsten
Hielscher, Thomas
Seifert, Marc
Küppers, Ralf
Assenov, Yassen
Lutsik, Pavlo
Stilgenbauer, Stephan
Roessner, Philipp M
Seiffert, Martina
Byrd, John
Oakes, Christopher C
Plass, Christoph
Lipka, Daniel B
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_07bff21ec86d48ca9abc2144570ae521
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_07bff21ec86d48ca9abc2144570ae521
Other Identifiers
ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-020-00724-7
