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ArticlesPeer ReviewedFull Text
Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib
Author / Creator:Woyach, Jennifer A ; Furman, Richard R ; Liu, Ta-Ming ; Ozer, Hatice Gulcin ; Zapatka, Marc ; Ruppert, Amy S ; Xue, Ling ; Li, Daniel Hsieh-Hsin ; Steggerda, Susanne M ; Versele, Matthias ; Dave, Sandeep S ; Zhang, Jenny ; Yilmaz, Ayse Selen ; Jaglowski, Samantha M ; Blum, Kristie A ; Lozanski, Arletta ; Lozanski, Gerard ; James, Danelle F ; Barrientos, Jacqueline C ; Lichter, Peter ; Stilgenbauer, Stephan ; Buggy, Joseph J ; Chang, Betty Y ; Johnson, Amy J ; Byrd, John C
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-06, Vol.370 (24), p.2286-2294
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Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions
Author / Creator:Fischer, Kirsten ; Al-Sawaf, Othman ; Bahlo, Jasmin ; Fink, Anna-Maria ; Tandon, Maneesh ; Dixon, Mark ; Robrecht, Sandra ; Warburton, Simon ; Humphrey, Kathryn ; Samoylova, Olga ; Liberati, Anna M ; Pinilla-Ibarz, Javier ; Opat, Stephen ; Sivcheva, Liliya ; Le Dû, Katell ; Fogliatto, Laura M ; Niemann, Carsten U ; Weinkove, Robert ; Robinson, Sue ; Kipps, Thomas J ; Boettcher, Sebastian ; Tausch, Eugen ; Humerickhouse, Rod ; Eichhorst, Barbara ; Wendtner, Clemens-Martin ; Langerak, Anton W ; Kreuzer, Karl-Anton ; Ritgen, Matthias ; Goede, Valentin ; Stilgenbauer, Stephan ; Mobasher, Mehrdad ; Hallek, Michael
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-06, Vol.380 (23), p.2225-2236
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ArticlesPeer ReviewedFull Text
Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm
Author / Creator:Scheffold, Annika ; Stilgenbauer, Stephan
Publisher:New York: Springer US
Journal title:Current oncology reports, 2020-02, Vol.22 (2), p.16-16, Article 16
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ArticlesPeer ReviewedFull Text
repDilPCR: a tool for automated analysis of qPCR assays by the dilution-replicate method
Author / Creator:Yosifov, Deyan Yordanov ; Reichenzeller, Michaela ; Stilgenbauer, Stephan ; Mertens, Daniel
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2024-10, Vol.25 (1), p.331-13, Article 331
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Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia
Author / Creator:Furman, Richard R ; Sharman, Jeff P ; Coutre, Steven E ; Cheson, Bruce D ; Pagel, John M ; Hillmen, Peter ; Barrientos, Jacqueline C ; Zelenetz, Andrew D ; Kipps, Thomas J ; Flinn, Ian ; Ghia, Paolo ; Eradat, Herbert ; Ervin, Thomas ; Lamanna, Nicole ; Coiffier, Bertrand ; Pettitt, Andrew R ; Ma, Shuo ; Stilgenbauer, Stephan ; Cramer, Paula ; Aiello, Maria ; Johnson, Dave M ; Miller, Langdon L ; Li, Daniel ; Jahn, Thomas M ; Dansey, Roger D ; Hallek, Michael ; O'Brien, Susan M
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-03, Vol.370 (11), p.997-1007
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ArticlesPeer ReviewedFull Text
Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions
Author / Creator:Goede, Valentin ; Fischer, Kirsten ; Busch, Raymonde ; Engelke, Anja ; Eichhorst, Barbara ; Wendtner, Clemens M ; Chagorova, Tatiana ; de la Serna, Javier ; Dilhuydy, Marie-Sarah ; Illmer, Thomas ; Opat, Stephen ; Owen, Carolyn J ; Samoylova, Olga ; Kreuzer, Karl-Anton ; Stilgenbauer, Stephan ; Döhner, Hartmut ; Langerak, Anton W ; Ritgen, Matthias ; Kneba, Michael ; Asikanius, Elina ; Humphrey, Kathryn ; Wenger, Michael ; Hallek, Michael
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-03, Vol.370 (12), p.1101-1110
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Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3...
Author / Creator:Al-Sawaf, Othman, MD ; Zhang, Can, PhD ; Tandon, Maneesh, MD ; Sinha, Arijit, PhD ; Fink, Anna-Maria, MD ; Robrecht, Sandra, PhD ; Samoylova, Olga, MD ; Liberati, Anna M, MD ; Pinilla-Ibarz, Javier, MD ; Opat, Stephen, MD ; Sivcheva, Liliya, MD ; Le Dû, Katell, MD ; Fogliatto, Laura M, MD ; Niemann, Carsten U, MD ; Weinkove, Robert, MD ; Robinson, Sue, MD ; Kipps, Thomas J, Prof ; Tausch, Eugen, MD ; Schary, William, PhD ; Ritgen, Matthias, MD ; Wendtner, Clemens-Martin, MD ; Kreuzer, Karl-Anton, MD ; Eichhorst, Barbara, MD ; Stilgenbauer, Stephan, Prof ; Hallek, Michael, Prof ; Fischer, Kirsten, MD
Publisher:London: Elsevier Ltd
Journal title:The lancet oncology, 2020-09, Vol.21 (9), p.1188-1200
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ArticlesPeer ReviewedFull Text
Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma
Author / Creator:Wang, Michael L ; Rule, Simon ; Martin, Peter ; Goy, Andre ; Auer, Rebecca ; Kahl, Brad S ; Jurczak, Wojciech ; Advani, Ranjana H ; Romaguera, Jorge E ; Williams, Michael E ; Barrientos, Jacqueline C ; Chmielowska, Ewa ; Radford, John ; Stilgenbauer, Stephan ; Dreyling, Martin ; Jedrzejczak, Wieslaw Wiktor ; Johnson, Peter ; Spurgeon, Stephen E ; Li, Lei ; Zhang, Liang ; Newberry, Kate ; Ou, Zhishuo ; Cheng, Nancy ; Fang, Bingliang ; McGreivy, Jesse ; Clow, Fong ; Buggy, Joseph J ; Chang, Betty Y ; Beaupre, Darrin M ; Kunkel, Lori A ; Blum, Kristie A
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-08, Vol.369 (6), p.507-516
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ArticlesPeer ReviewedFull Text
Renal AA amyloidosis leading to early diagnosis and treatment of takayasu arteritis: a case report and review of the literature
Author / Creator:Kos, Igor ; Stilgenbauer, Stephan ; Bewarder, Moritz
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Clinical research in cardiology, 2020-11, Vol.109 (11), p.1438-1441
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Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study
Author / Creator:Stilgenbauer, Stephan, Prof ; Eichhorst, Barbara, Prof ; Schetelig, Johannes, Prof ; Coutre, Steven, Prof ; Seymour, John F, Prof ; Munir, Talha, Prof ; Puvvada, Soham D, MD ; Wendtner, Clemens-Martin, Prof ; Roberts, Andrew W, Prof ; Jurczak, Wojciech, Prof ; Mulligan, Stephen P, Prof ; Böttcher, Sebastian, MD ; Mobasher, Mehrdad, MD ; Zhu, Ming, PhD ; Desai, Monali, MD ; Chyla, Brenda, PhD ; Verdugo, Maria, MD ; Enschede, Sari Heitner, MD ; Cerri, Elisa, MD ; Humerickhouse, Rod, MD ; Gordon, Gary, MD ; Hallek, Michael, Prof ; Wierda, William G, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.768-778
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First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic leukaemia (CLL10): an international, ope...
Author / Creator:Eichhorst, Barbara, Dr ; Fink, Anna-Maria, MD ; Bahlo, Jasmin, PhD ; Busch, Raymonde, Dipl Math ; Kovacs, Gabor, MD ; Maurer, Christian, MD ; Lange, Elisabeth, MD ; Köppler, Hubert, Prof ; Kiehl, Michael, Prof ; Sökler, Martin, MD ; Schlag, Rudolf, MD ; Vehling-Kaiser, Ursula, MD ; Köchling, Georg, MD ; Plöger, Christoph, MD ; Gregor, Michael, MD ; Plesner, Torben, MD ; Trneny, Marek, Prof ; Fischer, Kirsten, MD ; Döhner, Harmut, Prof ; Kneba, Michael, Prof ; Wendtner, Clemens-Martin, Prof ; Klapper, Wolfram, Prof ; Kreuzer, Karl-Anton, Prof ; Stilgenbauer, Stephan, Prof ; Böttcher, Sebastian, MD ; Hallek, Michael, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-07, Vol.17 (7), p.928-942
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Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia
Author / Creator:Al-Sawaf, Othman ; Zhang, Can ; Jin, Hyun Yong ; Robrecht, Sandra ; Choi, Yoonha ; Balasubramanian, Sandhya ; Kotak, Alex ; Chang, Yi Meng ; Fink, Anna Maria ; Tausch, Eugen ; Schneider, Christof ; Ritgen, Matthias ; Kreuzer, Karl-Anton ; Chyla, Brenda ; Paulson, Joseph N. ; Pallasch, Christian P. ; Frenzel, Lukas P. ; Peifer, Martin ; Eichhorst, Barbara ; Stilgenbauer, Stephan ; Jiang, Yanwen ; Hallek, Michael ; Fischer, Kirsten
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.2147-2147, Article 2147
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Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations
Author / Creator:Wierda, William G. ; Rawstron, Andrew ; Cymbalista, Florence ; Badoux, Xavier ; Rossi, Davide ; Brown, Jennifer R. ; Egle, Alexander ; Abello, Virginia ; Cervera Ceballos, Eduardo ; Herishanu, Yair ; Mulligan, Stephen P. ; Niemann, Carsten U. ; Diong, Colin P. ; Soysal, Teoman ; Suzuki, Ritsuro ; Tran, Hoa T. T. ; Wu, Shang-Ju ; Owen, Carolyn ; Stilgenbauer, Stephan ; Ghia, Paolo ; Hillmen, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-11, Vol.35 (11), p.3059-3072
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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
Author / Creator:Oakes, Christopher C ; Seifert, Marc ; Assenov, Yassen ; Gu, Lei ; Przekopowitz, Martina ; Ruppert, Amy S ; Wang, Qi ; Imbusch, Charles D ; Serva, Andrius ; Koser, Sandra D ; Brocks, David ; Lipka, Daniel B ; Bogatyrova, Olga ; Weichenhan, Dieter ; Brors, Benedikt ; Rassenti, Laura ; Kipps, Thomas J ; Mertens, Daniel ; Zapatka, Marc ; Lichter, Peter ; Döhner, Hartmut ; Küppers, Ralf ; Zenz, Thorsten ; Stilgenbauer, Stephan ; Byrd, John C ; Plass, Christoph
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2016-03, Vol.48 (3), p.253-264
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Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study
Author / Creator:O'Brien, Susan, Prof ; Jones, Jeffrey A, MD ; Coutre, Steven E, Prof ; Mato, Anthony R, MD ; Hillmen, Peter, Prof ; Tam, Constantine, MD ; Österborg, Anders, Prof ; Siddiqi, Tanya, MD ; Thirman, Michael J, MD ; Furman, Richard R, MD ; Ilhan, Osman, Prof ; Keating, Michael J, Prof ; Call, Timothy G, MD ; Brown, Jennifer R, MD ; Stevens-Brogan, Michelle, MSc ; Li, Yunfeng, PhD ; Clow, Fong, ScD ; James, Danelle F, MD ; Chu, Alvina D, MD ; Hallek, Michael, Prof ; Stilgenbauer, Stephan, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-10, Vol.17 (10), p.1409-1418
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Idelalisib or placebo in combination with bendamustine and rituximab in patients with relapsed or refractory chronic lymphocytic leukaemia: interim results from a phase 3, randomised, double-blind, pl...
Author / Creator:Zelenetz, Andrew D, Prof ; Barrientos, Jacqueline C, MD ; Brown, Jennifer R, MD ; Coiffier, Bertrand, Prof ; Delgado, Julio, MD ; Egyed, Miklós, Prof ; Ghia, Paolo, MD ; Illés, Árpád, Prof ; Jurczak, Wojciech, MD ; Marlton, Paula, MBBS ; Montillo, Marco, MD ; Morschhauser, Franck, Prof ; Pristupa, Alexander S, MD ; Robak, Tadeusz, Prof ; Sharman, Jeff P, MD ; Simpson, David, MBChB ; Smolej, Lukáš, MD ; Tausch, Eugen, MD ; Adewoye, Adeboye H, MD ; Dreiling, Lyndah K, MD ; Kim, Yeonhee, PhD ; Stilgenbauer, Stephan, Prof ; Hillmen, Peter, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-03, Vol.18 (3), p.297-311
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Current Treatment Options in CLL
Author / Creator:Bewarder, Moritz ; Stilgenbauer, Stephan ; Thurner, Lorenz ; Kaddu-Mulindwa, Dominic
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-05, Vol.13 (10), p.2468
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EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia
Author / Creator:Llaó-Cid, Laura ; Roessner, Philipp M. ; Chapaprieta, Vicente ; Öztürk, Selcen ; Roider, Tobias ; Bordas, Marie ; Izcue, Ana ; Colomer, Dolors ; Dietrich, Sascha ; Stilgenbauer, Stephan ; Hanna, Bola ; Martín-Subero, José Ignacio ; Seiffert, Martina
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-11, Vol.35 (11), p.3152-3162
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FDG PET/CT to detect bone marrow involvement in the initial staging of patients with aggressive non-Hodgkin lymphoma: results from the prospective, multicenter PETAL and OPTIMAL>60 trials
Author / Creator:Kaddu-Mulindwa, Dominic ; Altmann, Bettina ; Held, Gerhard ; Angel, Stephanie ; Stilgenbauer, Stephan ; Thurner, Lorenz ; Bewarder, Moritz ; Schwier, Maren ; Pfreundschuh, Michael ; Löffler, Markus ; Menhart, Karin ; Grosse, Jirka ; Ziepert, Marita ; Herrmann, Ken ; Dührsen, Ulrich ; Hüttmann, Andreas ; Barbato, Francesco ; Poeschel, Viola ; Hellwig, Dirk
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of nuclear medicine and molecular imaging, 2021-10, Vol.48 (11), p.3550-3559
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Early treatment with FCR versus watch and wait in patients with stage Binet A high-risk chronic lymphocytic leukemia (CLL): a randomized phase 3 trial
Author / Creator:Herling, Carmen D. ; Cymbalista, Florence ; Groß-Ophoff-Müller, Carolin ; Bahlo, Jasmin ; Robrecht, Sandra ; Langerbeins, Petra ; Fink, Anna-Maria ; Al-Sawaf, Othman ; Busch, Raymonde ; Porcher, Raphael ; Cazin, Bruno ; Dreyfus, Brigitte ; Ibach, Stefan ; Leprêtre, Stéphane ; Fischer, Kirsten ; Kaiser, Florian ; Eichhorst, Barbara ; Wentner, Clemens-Martin ; Hoechstetter, Manuela A. ; Döhner, Hartmut ; Leblond, Veronique ; Kneba, Michael ; Letestu, Remi ; Böttcher, Sebastian ; Stilgenbauer, Stephan ; Hallek, Michael ; Levy, Vincent
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-08, Vol.34 (8), p.2038-2050
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Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib

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Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions

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Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm

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repDilPCR: a tool for automated analysis of qPCR assays by the dilution-replicate method

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Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia

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Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

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Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3...

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Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma

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Renal AA amyloidosis leading to early diagnosis and treatment of takayasu arteritis: a case report and review of the literature

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Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study

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First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic leukaemia (CLL10): an international, ope...

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Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia

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Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations

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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

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Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study

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Idelalisib or placebo in combination with bendamustine and rituximab in patients with relapsed or refractory chronic lymphocytic leukaemia: interim results from a phase 3, randomised, double-blind, pl...

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Current Treatment Options in CLL

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EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia

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FDG PET/CT to detect bone marrow involvement in the initial staging of patients with aggressive non-Hodgkin lymphoma: results from the prospective, multicenter PETAL and OPTIMAL>60 trials

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Early treatment with FCR versus watch and wait in patients with stage Binet A high-risk chronic lymphocytic leukemia (CLL): a randomized phase 3 trial

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