Strategies to reduce sample sizes in Alzheimer's disease primary and secondary prevention trials usi...
Strategies to reduce sample sizes in Alzheimer's disease primary and secondary prevention trials using longitudinal amyloid PET imaging
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Author / Creator
Lopes Alves, Isadora , Heeman, Fiona , Collij, Lyduine E , Salvadó, Gemma , Tolboom, Nelleke , Vilor-Tejedor, Natàlia , Markiewicz, Pawel , Yaqub, Maqsood , Cash, David , Mormino, Elizabeth C , Insel, Philip S , Boellaard, Ronald , van Berckel, Bart N M , Lammertsma, Adriaan A , Barkhof, Frederik and Gispert, Juan Domingo
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer's disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic imaging) and regional quantitative values could improve statis...
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Full title
Strategies to reduce sample sizes in Alzheimer's disease primary and secondary prevention trials using longitudinal amyloid PET imaging
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TN_cdi_doaj_primary_oai_doaj_org_article_082c31a7af464c6799346086b3dce7a1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_082c31a7af464c6799346086b3dce7a1
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ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-021-00819-2