Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation
Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Uhrf1-dependent histone H3 ubiquitylation plays a crucial role in the maintenance of DNA methylation via the recruitment of the DNA methyltransferase Dnmt1 to DNA methylation sites. However, the involvement of deubiquitylating enzymes (DUBs) targeting ubiquitylated histone H3 in the maintenance of DNA methylation is largely unknown. With the use of...
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Full title
Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation
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TN_cdi_doaj_primary_oai_doaj_org_article_08433a10a663408cb2881ea8919a7717
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08433a10a663408cb2881ea8919a7717
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-00136-5
