Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics
Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics
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Author / Creator
Serrano-Lopez, Juana , Hegde, Shailaja , Kumar, Sachin , Serrano, Josefina , Fang, Jing , Wellendorf, Ashley M , Roche, Paul A , Rangel, Yamileth , Carrington, Leolene J , Geiger, Hartmut , Grimes, H Leighton , Luther, Sanjiv , Maillard, Ivan , Sanchez-Garcia, Joaquin , Starczynowski, Daniel T and Cancelas, Jose A
Publisher
England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Innate immune cellular effectors are actively consumed during systemic inflammation, but the systemic traffic and the mechanisms that support their replenishment remain unknown. Here, we demonstrate that acute systemic inflammation induces the emergent activation of a previously unrecognized system of rapid migration of granulocyte-macrophage proge...
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Full title
Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics
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TN_cdi_doaj_primary_oai_doaj_org_article_08b4f0f9fe184ce5b3fbfcccc7aca175
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08b4f0f9fe184ce5b3fbfcccc7aca175
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.66190