Improved polygenic prediction by Bayesian multiple regression on summary statistics
Improved polygenic prediction by Bayesian multiple regression on summary statistics
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Accurate prediction of an individual’s phenotype from their DNA sequence is one of the great promises of genomics and precision medicine. We extend a powerful individual-level data Bayesian multiple regression model (BayesR) to one that utilises summary statistics from genome-wide association studies (GWAS), SBayesR. In simulation and cross-validat...
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Improved polygenic prediction by Bayesian multiple regression on summary statistics
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TN_cdi_doaj_primary_oai_doaj_org_article_08ca063725f844dd8f1661fc58a72c97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08ca063725f844dd8f1661fc58a72c97
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12653-0
