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Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08e7c695e7a0496dbcbb93d281626f1b

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

About this item

Full title

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-06, Vol.9 (1), p.2547-15, Article 2547

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Emerging evidence has illustrated the importance of epigenomic reprogramming in cancer, with altered post-translational modifications of histones contributing to pathogenesis. However, the contributions of histone modifiers to breast cancer progression are unclear, and how these processes vary between molecular subtypes has yet to be adequately add...

Alternative Titles

Full title

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_08e7c695e7a0496dbcbb93d281626f1b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_08e7c695e7a0496dbcbb93d281626f1b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-04864-8

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