The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in...
The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Circulating CCR2
+
monocytes are crucial for maintaining the adult tissue-resident F4/80
hi
MHCII
hi
macrophage pool in the intestinal lamina propria. Here we show that a subpopulation of CCR2-independent F4/80
hi
MHCII
low
macrophages, which are the most abundant F4/80
hi
cells in neonates, gradually decline in...
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Full title
The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma
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TN_cdi_doaj_primary_oai_doaj_org_article_095c4870307447429bbbc8eaff0cf1e6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_095c4870307447429bbbc8eaff0cf1e6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-02834-8