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The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in...

The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_095c4870307447429bbbc8eaff0cf1e6

The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma

About this item

Full title

The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-02, Vol.9 (1), p.582-13, Article 582

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Circulating CCR2
+
monocytes are crucial for maintaining the adult tissue-resident F4/80
hi
MHCII
hi
macrophage pool in the intestinal lamina propria. Here we show that a subpopulation of CCR2-independent F4/80
hi
MHCII
low
macrophages, which are the most abundant F4/80
hi
cells in neonates, gradually decline in...

Alternative Titles

Full title

The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_095c4870307447429bbbc8eaff0cf1e6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_095c4870307447429bbbc8eaff0cf1e6

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-02834-8

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