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Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogenei...

Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogenei...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_09d9e0ef2e924a438dede74c6b3805ed

Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

About this item

Full title

Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-11, Vol.14 (1), p.7717-7717, Article 7717

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pediatric high-grade gliomas of the subclass MYCN (HGG-MYCN) are highly aggressive tumors frequently carrying
MYCN
amplifications,
TP53
mutations, or both alterations. Due to their rarity, such tumors have only recently been identified as a distinct entity, and biological as well as clinical characteristics have not been addressed speci...

Alternative Titles

Full title

Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_09d9e0ef2e924a438dede74c6b3805ed

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_09d9e0ef2e924a438dede74c6b3805ed

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-43564-w

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