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A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a0891f37ae8435ba272d6d6816eeaf9

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

About this item

Full title

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

Publisher

London: Nature Publishing Group UK

Journal title

Molecular systems biology, 2014-08, Vol.10 (8), p.744-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Over the last decade, the field of cancer metabolism has mainly focused on studying the role of tumorigenic metabolic rewiring in supporting cancer proliferation. Here, we perform the first genome‐scale computational study of the metabolic underpinnings of cancer migration. We build genome‐scale metabolic models of the NCI‐60 cell lines that captur...

Alternative Titles

Full title

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0a0891f37ae8435ba272d6d6816eeaf9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a0891f37ae8435ba272d6d6816eeaf9

Other Identifiers

ISSN

1744-4292

E-ISSN

1744-4292

DOI

10.15252/msb.20134993

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