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Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a5157aefa5741f49d346794317e84b4

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

About this item

Full title

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

Publisher

London: BioMed Central

Journal title

Molecular neurodegeneration, 2020-11, Vol.15 (1), p.1-66, Article 66

Language

English

Formats

Publication information

Publisher

London: BioMed Central

More information

Scope and Contents

Contents

Background Alzheimer’s disease (AD) is the most common neurodegenerative disease and type 2 diabetes (T2D) plays an important role in conferring the risk for AD. Although AD and T2D share common features, the common molecular mechanisms underlying these two diseases remain elusive. Methods Mice with different AD- and/or tauopathy-linked genetic bac...

Alternative Titles

Full title

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0a5157aefa5741f49d346794317e84b4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a5157aefa5741f49d346794317e84b4

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-020-00415-2

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