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Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem...

Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a5d14d83c0d45119b67eeb0035dc63b

Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells

About this item

Full title

Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2023-05, Vol.6 (1), p.558-558, Article 558

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Single-cell approaches have revealed that the haematopoietic hierarchy is a continuum of differentiation, from stem cell to committed progenitor, marked by changes in gene expression. However, many of these approaches neglect isoform-level information and thus do not capture the extent of alternative splicing within the system. Here, we present an...

Alternative Titles

Full title

Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0a5d14d83c0d45119b67eeb0035dc63b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a5d14d83c0d45119b67eeb0035dc63b

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-023-04936-6

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