Identification of Piperlongumine as Potent Inhibitor of Necroptosis
Identification of Piperlongumine as Potent Inhibitor of Necroptosis
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Author / Creator
He, Xiaoyan , Li, Min , Ye, Zhi , You, Xiaoling , Wang, Jia , Xiao, Xin , Zhu, Guofeng , Wei, Jun and Zha, Yunhong
Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
Formats
Publication information
Publisher
New Zealand: Dove Medical Press Limited
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Scope and Contents
Contents
Excessive necroptosis contributes to the pathogenesis of several inflammatory and neurodegenerative diseases. Here, using a high-throughput screening approach, we investigated the anti-necroptosis effects of piperlongumine, an alkaloid isolated from the long pepper plant, in vitro and in a mouse model of systemic inflammatory response syndrome (SIR...
Alternative Titles
Full title
Identification of Piperlongumine as Potent Inhibitor of Necroptosis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0a85a5a87de94e4d908687325c5e254d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a85a5a87de94e4d908687325c5e254d
Other Identifiers
ISSN
1177-8881
E-ISSN
1177-8881
DOI
10.2147/DDDT.S397971
