Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic l...
Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS)
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United States: Public Library of Science (PLoS)
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English
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United States: Public Library of Science (PLoS)
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The human SOD1(G93A) transgenic mouse has been used extensively since its development in 1994 as a model for amyotrophic lateral sclerosis (ALS). In that time, a great many insights into the toxicity of mutant SOD1 have been gained using this and other mutant SOD transgenic mouse models. They all demonstrate a selective toxicity towards motor neuro...
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Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS)
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TN_cdi_doaj_primary_oai_doaj_org_article_0a8e58065d064ae8ae3e91567ca6ba0c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a8e58065d064ae8ae3e91567ca6ba0c
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023244
