Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Accumulating evidence implicates impairment of the autophagy‐lysosome pathway in Alzheimer's disease (AD). Recently discovered, transcription factor EB (TFEB) is a molecule shown to play central roles in cellular degradative processes. Here we investigate the role of TFEB in AD mouse models. In this study, we demonstrate that TFEB effectively reduc...
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Full title
Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
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TN_cdi_doaj_primary_oai_doaj_org_article_0b108629476c462dadc2e36ff5876d08
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b108629476c462dadc2e36ff5876d08
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201303671
