Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-relate...
Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In
EGFR
-mutated lung cancer, the duration of response to tyrosine kinase inhibitors (TKIs) is limited by the development of acquired drug resistance. Despite the crucial role played by apoptosis-related genes in tumor cell survival, how their expression changes as resistance to EGFR-TKIs emerges remains unclear. Here, we conduct a comprehens...
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Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_0b4880c0b7b44dc7aa9de281cdad4388
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b4880c0b7b44dc7aa9de281cdad4388
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2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06940-y